STK receptor tyrosine kinase regulates susceptibility to infection with Listeria monocytogenes.
نویسندگان
چکیده
We have previously identified the STK receptor tyrosine kinase as a key regulator of macrophage activation and cell-mediated immune responses. Here we demonstrate that, although MSP activation of STK inhibits NO production by macrophages in response to heat-killed Listeria monocytogenes, STK-deficient mice exhibit increased susceptibility to infection with Listeria.
منابع مشابه
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ورودعنوان ژورنال:
- Infection and immunity
دوره 70 1 شماره
صفحات -
تاریخ انتشار 2002